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What is Osteogenesis Imperfecta? Osteogenesis imperfecta (OI) is a genetic disorder characterized by bones that break easily. The bones often break from little or no apparent cause. Most adults and children with osteogenesis imperfecta lead productive and successful lives. What Causes Osteogenesis Imperfecta? Osteogenesis imperfecta is caused by a genetic defect that affects the bodys production of collagen. Collagen is the major protein of the bodys connective tissue. When a person has osteogenesis imperfecta, their body produces either less collagen than normal, or a poorer quality of collagen than normal. Types of Osteogenesis Imperfecta? There are four main types of the disorder
Can Osteogenesis Imperfecta be Treated? Currently, there is not yet a cure for osteogenesis imperfecta. Treatment is directed toward preventing or controlling the symptoms, maximizing independent mobility, and developing optimal bone mass and muscle strength. The most common treatments are: extensive surgical and dental procedures, and physical therapy. Use of wheelchairs, braces, and other mobility aids are common. |
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